MODERN VIEW TO OPTIMIZATION OF DIAGNOSTICS OF PARKINSON'S DISEASE

Daminova Hilola Maratovna

doi:10.61796/jmgcb.v1i6.617

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Daminova Hilola Maratovna
Maratovna@Gmail.com
Tashkent Medical Academy

Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology

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June 13, 2024

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Parkinsonism is one of the most significant problems of clinical neurology, both due to its high prevalence in the world's populations and due to the significant disability of patients. The work analyzes the diagnosis of Parkinson's disease (as well as other neurodegenerative diseases) at the prodromal stage. A review of methods for preclinical and early clinical diagnosis of PD shows that the study of prodromal markers and criteria for the premotor phase of PD will make it possible in the future to significantly change the course of the disease using neuroprotective therapy at the stage preceding the death of a significant number of dopaminergic neurons of the substantia nigra.

Zakharov V.V. Neuropsychiatric disorders: diagnostic tests / V.V. Zakharov , T.G. Voznesenskaya – M.: MED press- inform , – 2013 – p.315.

Levin O.S. Diagnosis and treatment of dementia in clinical practice / O.S. Levin – M.: MEDpress-inform , – 2017. – p.254.

Litvinenko I.V. Neuroimaging in the diagnosis of nosological forms of parkinsonism and the possibility of predicting the course of Parkinson’s disease /I.V. Litvinenko, M.M. Odinak , A.G. Trufanov, V.A. Fokin, I.V. Boykov //Parkinson’s disease and movement disorders . p ed. S.N. Illarioshkina , O.S. Levina . – NCN RAMS – 2012. – p.113-130. 178

Braak H. Staging of brain pathology related to sporadic Parkinson's disease / Braak H., Del Tredici K., Rüb U., de Vos RAI, Jansen Steur ENH, Braak // Neurobiol Aging.–2003–Vol.24– p . 197 –210.

Nombela C. Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study / Nombela C., Rowe JB, Winder-Rhodes SE, Hampshire A., Owen AM, Breen DP, et al. //Brain. – 2014. – Vol. 137. – 2743-58.

Otero JL Dementia with Parkinson's disease Clinical diagnosis, neuropsychological aspects and treatment Dementia /Otero JL // Neuropsychologia –2018 – December –2(4) – p.261-266

Reid WGJ Dementia in Parkinson's disease: a 20-year neuropsychological study (Sydney Multicentre Study) / Reid WGJ, Hely MA, Morris JG L., Loy C., Halliday G. //J Neurol Neurosurg Psychiatry. – 2011. – Vol.82. – p. 1033.

Xu Y. Meta-analysis of risk factors for Parkinson's disease dementia. A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease / Xu Y., Yang J., Shang H. // Translational Neurodegeneration Neurodegener ] – 2016 – Jun 01 –Vol. 5 –p. eleven.