Focus and Scope

The Journal of Medical Genetics and Clinical Biology (JMGCB) is an international peer-reviewed journal dedicated to publishing high-quality research in medical genetics, clinical biology, genomics, molecular medicine, and translational biomedical sciences. The journal aims to advance scientific understanding of the genetic, molecular, and biological mechanisms underlying human health and disease, as well as their clinical application in diagnostics, therapeutics, disease prevention, and precision medicine.

JMGCB provides a scholarly platform for clinicians, geneticists, molecular biologists, bioinformaticians, laboratorians, and healthcare researchers to disseminate original findings and interdisciplinary studies that bridge laboratory discoveries with clinical practice and healthcare innovation.

The journal welcomes original research articles, systematic reviews, meta-analyses, short communications, case reports, and translational studies in, but not limited to, the following areas:

  • Clinical genomics and molecular diagnostics, including gene panels, whole-exome sequencing (WES), whole-genome sequencing (WGS), structural variant analysis, and clinical variant interpretation
  • Mendelian and complex genetic disorders, including genotype–phenotype correlations, disease susceptibility, penetrance, and modifier studies
  • Cancer genetics and precision oncology, including hereditary cancer syndromes, tumor genomics, molecular biomarkers, and targeted therapies
  • Pharmacogenomics and personalized therapeutics, including genotype-guided treatment strategies and precision prescribing
  • Biomarkers and translational medicine, including prognostic, predictive, and companion diagnostic studies
  • Reproductive, prenatal, neonatal, and pediatric genetics, including carrier screening, NIPT, and newborn screening
  • Population, community, and public-health genomics, including ancestry studies, genomic epidemiology, and implementation of genomic medicine
  • Bioinformatics, computational biology, artificial intelligence, and clinical decision-support systems in genomic medicine
  • Multi-omics integration, including transcriptomics, epigenomics, proteomics, metabolomics, and systems biology approaches
  • Gene therapy, cell-based therapeutics, genome editing, and clinically oriented functional validation studies
  • Clinical biology and translational biomedical sciences, including molecular pathology, immunology, inflammation, metabolism, and disease mechanisms
  • Clinical microbiology, microbiome research, and host–microbe genomics related to disease progression and therapeutic outcomes
  • Ethical, legal, and social implications (ELSI) of genetics and genomics, including genetic counseling, privacy, consent, and policy studies
  • Implementation science, healthcare innovation, and outcomes research related to genomic and precision medicine
  • Education and training in medical genetics, clinical biology, and genomic healthcare practice

 

JMGCB particularly encourages interdisciplinary and translational studies with clear clinical relevance and potential impact on patient care, public health, and precision healthcare systems worldwide.