IN VITRO ANTIBACTERIAL ACTIVITY OF AQUEOUS EXTRACT OF CRANBERRY (VACCINIUM MACROCARPON) AGAINST E. COLI ISOLATED FROM URINARY TRACT INFECTION

Ruqayyah Hussein Kazim Ghulam; Milad Munther Zahid Baniya; Adyan abd Al_khalq aziz nema; Messad Hammad Kadhim Edam; Muslim Hakim Nahi Thaher

doi:10.61796/jmgcb.v1i8.821

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Ruqayyah Hussein Kazim Ghulam
kedm27443@gmail.com
Al-Farabi University College / Department of Biological Life Sciences
Milad Munther Zahid Baniya University of Kufa College of Science Department of Biology
Adyan abd Al_khalq aziz nema University of Kufa College of Science Department of Biology
Messad Hammad Kadhim Edam University of Muthanna, College of Science, Department of Life Sciences ( Biology )
Muslim Hakim Nahi Thaher University of Muthanna, College of Science, Department of Life Sciences ( Biology )

Vol. 1 No. 8 (2024): Journal of Medical Genetics and Clinical Biology

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August 7, 2024

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The present study was carried out to investigate in-vitro antibacterial activity of aqueous extract of Cranberry (Vaccinium macrocarpon) fruit against Escherichia coli isolated from urinary tract infection. The present study included two experiment; the first one is isolate and identify of E. coli; the second experiment include study in-vitro antibacterial activity of aqueous extract of Cranberry, consisting two steps, the first step involved collection of Cranberry fruit then they were identified and then squeezed by an electric mixer to obtain the aqueous extract. The fruit extract then dried. The second step was to study the in vitro antibacterial activity of Cranberry aqueous extract including minimum inhibitory concentration (MIC) against E. coli used as reference antibiotics. The yielding percentage of Cranberry (Vaccinium macrocarpon) fruit extract was (30%). The in-vitro antibacterial study showed the Cranberry aqueous extract was more effective than Gentamicin against E.coli, this organism was quite resistant to Ciprofloxacin. It could be concluded however that Cranberry aqueous extract was more effective in comparison with the standard antibacterial agent, and that the antibacterial activity of Cranberry aqueous extracts against urinary tract infection may be attributed to its essential particularly the important phenolic compound (Proanthocyanidin).

Ghulam, R. H. K., Baniya, M. M. Z., nema, A. abd A. aziz, Edam, M. H. K., & Thaher, M. H. N. (2024). IN VITRO ANTIBACTERIAL ACTIVITY OF AQUEOUS EXTRACT OF CRANBERRY (VACCINIUM MACROCARPON) AGAINST E. COLI ISOLATED FROM URINARY TRACT INFECTION. Journal of Medical Genetics and Clinical Biology, 1(8), 53–64. https://doi.org/10.61796/jmgcb.v1i8.821

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Journal of Medical Genetics and Clinical Biology

IN VITRO ANTIBACTERIAL ACTIVITY OF AQUEOUS EXTRACT OF CRANBERRY (VACCINIUM MACROCARPON) AGAINST E. COLI ISOLATED FROM URINARY TRACT INFECTION

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