Article Sidebar

Download
View Article
Statistic
Read Counter : 12 Download : 14

Main Article Content

Abstract

Background: Infertility treatments significantly impact the quality of life for women, with poor psychological well-being often leading to higher rates of treatment discontinuation. Specific Background: In vitro fertilization (IVF) is a common intervention for genetically infertile women, yet its effects on quality of life remain underexplored, particularly using comprehensive tools like the Fertility Quality of Life Questionnaire (FERTIQOL). Knowledge Gap: Previous studies have not thoroughly assessed the impact of IVF on quality of life using FERTIQOL among genetically infertile women in specific geographic locations, such as Iraq. Aims: This study aims to evaluate the FERTIQOL among genetically infertile women undergoing IVF to determine its impact on their quality of life. Results: A total of 75 genetically infertile women, aged 20-45 years, were recruited from Baghdad hospitals between April 6, 2023, and October 10, 2024. The study found a 64% prevalence of primary infertility and a 36% prevalence of secondary infertility. Post-IVF complications occurred in 25.33% of cases, and pregnancy loss was reported in 32% of patients. Hormonal levels were recorded as follows: FSH 6.58 ± 0.05 IU/L, LH 6.52 ± 0.61 IU/L, estradiol 161.92 ± 6.18 pmol/L, and progesterone 0.89 ± 0.48 nmol/L. The FERTIQOL scores revealed a mean tolerability score of 76.55 ± 13.20, a treatment FertiQoL score of 67.91 ± 10.83, a relational score of 60.02 ± 8.74, and a Mind/Body score of 68.78 ± 16.59. Novelty: This study is among the first to assess the impact of IVF on quality of life in genetically infertile women using FERTIQOL in an Iraqi setting. Implications: The findings highlight the significant role of IVF in managing genetic infertility and its profound impact on patients' quality of life, underscoring the need for comprehensive support systems during treatment.

Keywords

Infertile women Symptoms General health - QOL Genetic factor Vitro fertilization

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite
Salman, D. A. A. M. ., Khalaf, D. A. K., & Shareef, D. R. M. (2024). IMPROVING QUALITY OF LIFE FOR WOMEN WITH GENETIC-RELATED INFERTILITY. Journal of Medical Genetics and Clinical Biology, 1(8), 378–388. https://doi.org/10.61796/jmgcb.v1i8.902
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. Arslan‐Özkan, İ. , Okumuş, H. , & Buldukoğlu, K. (2014). A randomized controlled trial of the effects of nursing care based on Watson's Theory of Human Caring on distress, self‐efficacy, and adjustment in infertile women. Journal of Advanced Nursing, 70 (8), 1801–1812.
  2. Bayar, U. , Basaran, M. , Atasoy, N. , Kokturk, F. , Arikan, I. I. , Barut, A. , & Harma, M. (2014). Sexual dysfunction in infertile couples: Evaluation and treatment of infertility. Sexual dysfunction. Journal of the Pakistan Medical Association, 64, 138–145.
  3. Bokaie, M. , Simbar, M. , & Ardekani, S. M. Y. (2015). Sexual behavior of infertile women: A qualitative study. Iranian Journal of Reproductive Medicine, 13 (10), 645.
  4. Bokaie, M. , Simbar, M. , Ardekani, S. M. Y. , & Majd, H. A. (2016). Women's beliefs about infertility and sexual behaviors: A qualitative study. Iranian Journal of Nursing and Midwifery Research, 21 (4), 379
  5. Chachamovich, J. R., Chachamovich, E., Ezer, H., Fleck, M. P., Knauth, D., & Passos, E. P. (2010). Investigating quality of life and health‐related quality of life in infertility: A systematic review. Journal of Psychosomatic Obstetrics & Gynecology, 31(2), 101–110.
  6. Cunha, M., Galhardo, A., & Pinto‐Gouveia, J. (2016). Experiential avoidance, self‐compassion, self‐judgment and coping styles in infertility. Sexual & Reproductive Healthcare, 10, 41–47.
  7. Datta, J., Palmer, M. J., Tanton, C., Gibson, L. J., Jones, K. G., Macdowall, W., … Wellings, K. (2016). Prevalence of infertility and help-seeking among 15,000 women and men. Human Reproduction, 31 (9), 2108–2118.
  8. Gerrits, T., Van Rooij, F., Esho, T., Ndegwa, W., Goossens, J., Bilajbegovic, A., & Migiro, S. K. (2017). Infertility in the Global South: Raising awareness and generating insights for policy and practice. Facts, Views & Vision in ObGyn, 9 (1), 39.
  9. Hadizadeh‐Talasaz, F., Latifnejad Roudsari, R., & Simbar, M. (2015). Decision for disclosure: The experiences of Iranian infertile couples undergoing assisted reproductive donation procedures. Human Fertility, 18 (4), 265–275.
  10. Hanson, B., Johnstone, E., Dorais, J., Silver, B., Peterson, C. M., & Hotaling, J. (2017). Female infertility, infertility‐associated diagnoses, and comorbidities: A review. Journal of Assisted Reproduction and Genetics, 34 (2), 167–177.
  11. Hasanpoor‐Azghady, S. B., Simbar, M., Vedadhir, A. A., Azin, S. A., & Amiri‐Farahani, L. (2019). The social construction of infertility among Iranian infertile women: A qualitative study. Journal of Reproduction & Infertility, 20 (3), 178.
  12. Hasanpoor‐Azghdy, S. B., Simbar, M., & Vedadhir, A. (2014). The emotional‐psychological consequences of infertility among infertile women seeking treatment: Results of a qualitative study. Iranian Journal of Reproductive Medicine, 12 (2), 131.
  13. Hasanpoor‐Azghdy, S. B., Simbar, M., & Vedadhir, A. (2015). The social consequences of infertility among Iranian women: A qualitative study. International Journal of Fertility & Sterility, 8 (4), 409.
  14. Jennings, P. K. (2010). ‘God had something else in mind’: Family, religion and infertility. Journal of Contemporary Ethnography, 39 (2), 215–237.
  15. Kiani, Z., & Simbar, M. (2019). Infertility's hidden and evident dimensions: A concern requiring special attention in Iranian Society. Iranian Journal of Public Health, 48 (11), 2114–2115.
  16. Kiani, Z., Simbar, M., Dolatian, M., & Zayeri, F. (2018). Women's empowerment in reproductive decision‐making needs attention among Iranian women. Iranian Journal of Public Health, 47 (3), 464.
  17. Kitchen, H., Aldhouse, N., Trigg, A., Palencia, R., & Mitchell, S. (2017). A review of patient‐reported outcome measures to assess female infertility‐related quality of life. Health and Quality of Life Outcomes, 15, 86 10.1186/s12955-017-0666-0
  18. Kleinheksel, A., Rockich‐Winston, N., Tawfik, H., & Wyatt, T. R. (2020). Demystifying content analysis. American Journal of Pharmaceutical Education, 84 (1), 7113 10.5688/ajpe7113 [PMC free article] [PubMed] [CrossRef] [Google Scholar]
  19. Kohan, S., Simbar, M., & Taleghani, F. (2012). Empowerment in family planning as viewed by Iranian women: A qualitative study. Journal of Biosocial Science, 44 (2), 209–219.
  20. Kura, S., Vince, J., & Crouch‐Chivers, P. (2013). Male involvement in sexual and reproductive health in the Mendi district, Southern Highlands province of Papua New Guinea: A descriptive study. Reproductive Health, 10 (1), 46
  21. Louis, J. F., Thoma, M. E., Sørensen, D. N., McLain, A. C., King, R. B., Sundaram, R., … Buck Louis, G. M. (2013). The prevalence of couple infertility in the United States from a male perspective: Evidence from a nationally representative sample. Andrology, 1 (5), 741–748.
  22. Maroufizadeh, S. , Karimi, E. , Vesali, S. , & Samani, R. O. (2015). Anxiety and depression after failure of assisted reproductive treatment among patients experiencing infertility. International Journal of Gynecology and Obstetrics, 130 (3), 253–256.
  23. Martins, M. V., Peterson, B., Almeida, V., Mesquita‐Guimarães, J., & Costa, M. (2014). Dyadic dynamics of perceived social support in couples facing infertility. Human Reproduction, 29 (1), 83–89.
  24. Morshed‐Behbahani, B., Lamyian, M., Joulaei, H., & Montazeri, A. (2020). Analysis and exploration of infertility policies in Iran: A study protocol. Health Research Policy and Systems, 18 (1), 1–7.
  25. Nachtigall, R. D. (2006). International disparities in access to infertility services. Fertility and Sterility, 85 (4), 871–875.
  26. Obiegło, M., Uchmanowicz, I., Wleklik, M., Jankowska‐Polańska, B., & Kuśmierz, M. (2016). The effect of acceptance of illness on the quality of life in patients with chronic heart failure. European Journal of Cardiovascular Nursing, 15 (4), 241–247.
  27. Onat, G. , & Beji, N. K. (2012). Marital relationship and quality of life among couples with infertility. Sexuality and Disability, 30 (1), 39–52.
  28. Oti‐Boadi, M., & Asante, K. O. (2017). Psychological health and religious coping of Ghanaian women with infertility. BioPsychoSocial Medicine, 11(1), 20 10.
  29. Katz, P. P. , & Adler, N. E. (2016). Addressing the needs of fertility treatment patients and their partners: Are they informed of and do they receive mental health services? Fertility and Sterility, 106 (1), 209–215.e2.
  30. Pasch, L. A., & Sullivan, K. T. (2017). Stress and coping in couples facing infertility. Current Opinion in Psychology, 13, 131–135.
  31. Pasha, H., Faramarzi, M., Esmailzadeh, S., Kheirkhah, F., & Salmalian, H. (2013). Comparison of pharmacological and nonpharmacological treatment strategies in the promotion of infertility self‐efficacy scale in infertile women: A randomized controlled trial. Iranian Journal of Reproductive Medicine, 11 (6), 495.
  32. Pour, T. H. (2014). The effect of cognitive behavioural therapy on anxiety in infertile women. European Journal of Experimental Biology, 4 (1), 415–419.
  33. Ritchie, J., Lewis, J., Nicholls, C. M., & Ormston, R. (2013). Designing and selecting samples Metzir K. Qualitative research practice: A guide for social science students and researchers, 10, 9, (111–142). Thousand Oaks, CA: Sage.
  34. Rooney, K. L., & Domar, A. D. (2018). The relationship between stress and infertility. Dialogues in Clinical Neuroscience, 20 (1), 41.
  35. Taebi, M., Simbar, M., & Abdolahian, S. (2018). Psychological empowerment strategies in infertile women: A systematic review. Journal of Education and Health Promotion, 7, 68.
  36. Yao, H., Chan, C. H. Y., & Chan, C. L. W. (2018). Childbearing importance: A qualitative study of women with infertility in China. Research in Nursing & Health, 41 (1), 69–77.