MULTIFORM EXUDATIVE ERYTHEMA OF THE ORAL MUCOSA: DIAGNOSIS AND COMPREHENSIVE TREATMENT

Gurbanov Ramin Yagub; Huseynova Mehriban Khalil; Ibragimov Elshad Agaveli

doi:10.61796/jmgcb.v3i2.1611

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Gurbanov Ramin Yagub
gurbanov@gmail.com
Azerbaijan Medical University, Azerbaijan
Huseynova Mehriban Khalil Azerbaijan Medical University, Azerbaijan
Ibragimov Elshad Agaveli Azerbaijan Medical University, Azerbaijan

Vol. 3 No. 2 (2026): Journal of Medical Genetics and Clinical Biology

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December 14, 2025

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Objective: This study aims to improve the diagnosis and comprehensive treatment of multiform exudative erythema (MEE) in patients through a developed treatment algorithm, evaluating both subjective and objective criteria of the oral mucosa and local humoral immunity. Method: A total of 81 patients with MEE were treated according to a developed treatment protocol, with 30 patients in a comparison group receiving traditional therapy. Patient assessments included clinical examinations, immunological testing (s-IgA, IL-6, phagocytic index), and dental quality-of-life indicators using the OHIP-14-RU questionnaire. The main group received the newly developed therapeutic algorithm, while the comparison group received traditional treatments. Results: The main group showed significant improvements in pain reduction, lesion healing, and oral mucosa condition compared to the comparison group. The OHIP-14-RU scores improved by 8 points in the main group, indicating enhanced quality of life. Novelty: The study introduces a new therapeutic-hygienic algorithm for MEE treatment, which results in faster healing, improved clinical and immunological parameters, and a significant improvement in oral health-related quality of life.

Yagub, G. R., Khalil, H. M., & Agaveli, I. E. (2025). MULTIFORM EXUDATIVE ERYTHEMA OF THE ORAL MUCOSA: DIAGNOSIS AND COMPREHENSIVE TREATMENT. Journal of Medical Genetics and Clinical Biology, 3(2), 111–117. https://doi.org/10.61796/jmgcb.v3i2.1611

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