RISK FACTORS FOR THE DEVELOPMENT OF RENAL PATHOLOGY, CARDIOVASCULAR AND CEREBROVASCULAR SYSTEMS

Mamurova Malikaxon Mirxamzayevna; Mamurova Mavludaxon Mirxamzayevna; Turayev Bobir Temirpulotovich

doi:10.61796/jmgcb.v2i4.1202

Authors

Mamurova Malikaxon Mirxamzayevna
mamurova@gmail.com
Doctor of Philosophy (PhD) of the Department of Medical Radiology, Samarkand State Medical University, Samarkand, Republic of Uzbekistan
Mamurova Mavludaxon Mirxamzayevna Doctor of Philosophy (PhD) of the Department of Neuralogy, Samarkand State Medical University, Samarkand, Republic of Uzbekistan
Turayev Bobir Temirpulotovich Assistant of the Department of Psychiatry, Mpsychology and Narcology, Samarkand State Medical University, Samarkand, Republic of Uzbekistan

Vol. 2 No. 4 (2025): Journal of Medical Genetics and Clinical Biology

Articles

January 24, 2025

Downloads

View Article

Abstract
How to Cite
Metrics
References
License

Objective: This study aims to identify and analyze common risk factors contributing to the development of renal pathology, cardiovascular diseases, and cerebrovascular disorders, highlighting the interconnected pathophysiological mechanisms among these systems. Method: A comprehensive literature review and comparative analysis were conducted to examine the overlapping pathogenetic pathways and shared risk factors across renal, cardiovascular, and cerebrovascular conditions. The study synthesized data from peer-reviewed articles, clinical studies, and epidemiological reports to identify key mechanisms influencing disease progression. Results: The analysis revealed that risk factors such as hypertension, diabetes mellitus, dyslipidemia, smoking, and chronic inflammation are common to all three systems, contributing to endothelial dysfunction, atherosclerosis, and impaired vascular regulation. These shared mechanisms underscore the parallel progression of pathology within the brain, heart, and kidneys, increasing the susceptibility to comorbid conditions. Novelty: This study provides new insights into the integrated pathophysiological processes linking renal, cardiovascular, and cerebrovascular diseases, emphasizing the need for holistic prevention strategies and multidisciplinary management approaches to address these interrelated health risks effectively.

Malikaxon Mirxamzayevna, M., Mavludaxon Mirxamzayevna, M., & Bobir Temirpulotovich, T. (2025). RISK FACTORS FOR THE DEVELOPMENT OF RENAL PATHOLOGY, CARDIOVASCULAR AND CEREBROVASCULAR SYSTEMS. Journal of Medical Genetics and Clinical Biology, 2(4), 70–78. https://doi.org/10.61796/jmgcb.v2i4.1202

Download Citation

A. Deutsch, N. Rodriguez, S. Roy, and J. S. Leventhal, “Treatment of persistent erythema multiforme with upadacitinib: A novel therapeutic approach,” JAAD Case Rep, vol. 34, pp. 70–73, Apr. 2023, doi: 10.1016/j.jdcr.2023.02.010.

Ц. ХЭ, “ОБЗОР ИССЛЕДОВАНИЙ ПО ОРГАНИЧЕСКОМУ МАРКСИЗМУ КИТАЙСКИХ АКАДЕМИЧЕСКИХ КРУГОВ ЗА ПОСЛЕДНИЕ ГОДЫ,” in ГЛОБАЛИСТИКА-2023, ISOASPSH of N.D. Kondratieff, Nov. 2024. doi: 10.46865/978-5-901640-41-8-2024-563-563.

A. N. Moskalenko, A. S. Filatov, Ey. Fedotova, R. N. Konovalov, and S. N. Illarioshkin, “Visual analysis of nigrosome-1 in the differential diagnosis of Parkinson’s disease and essential tremor,” Bulletin of Russian State Medical University, no. 2022(1), Jan. 2022, doi: 10.24075/brsmu.2022.002.

А. В. Митронин, М. Ю. Максимова, О. А. Антонова, Д. А. Останина, and В. А. Митронин, “СТОМАТОЛОГИЧЕСКИЙ СТАТУС ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ ИШЕМИЕЙ ГОЛОВНОГО МОЗГА,” MEDICINE, SCIENCE AND EDUCATION, no. 33, pp. 117–121, May 2022, doi: 10.56936/18291775-2022.33-117.

C. Guerri, “Neuroanatomical and Neurophysiological Mechanisms Involved in Central Nervous System Dysfunctions Induced by Prenatal Alcohol Exposure,” Alcoholism: Clinical & Experimental Research, vol. 22, no. 2, p. 15, Apr. 1998, doi: 10.1097/00000374-199804000-00003.

G. Vittadini, “ALCOHOLIC POLYNEUROPATHY: A CLINICAL AND EPIDEMIOLOGICAL STUDY,” Alcohol and Alcoholism, vol. 36, no. 5, pp. 393–400, Sep. 2001, doi: 10.1093/alcalc/36.5.393.

N. A. Tsalikova and A. T. Manukyan, “The effectiveness of the use of adaptogenic drugs for adaptation of patients with depressive neurosis to fixed orthopedic prosthetics.,” Stomatology for All / International Dental review, no. 1(110), pp. 54–57, Mar. 2025, doi: 10.35556/idr-2025-1(110)54-57.

J. J. Ross, “Reply to Gladstein,” Clinical Infectious Diseases, vol. 41, no. 1, pp. 128–129, Jul. 2005, doi: 10.1086/430838.

A. Pitman, “Temporal Risk Factors for Suicide After Suicide Bereavement,” in 2023 Intuition, Imagination and Innovation in Suicidology Conference, Založba Univerze na Primorskem, 2023, p. 15. doi: 10.26493/978-961-293-251-0.6.

A. M. Conjoh, Z. Zhou, and J. Xiong, “Socio-Cultural Factors Affecting the Spread of HIV/AIDS among Adolescents in Sierra Leone,” The Social Sciences, vol. 6, no. 4, pp. 269–276, Apr. 2011, doi: 10.3923/sscience.2011.269.276.

I. Belokrylov, “The Effectiveness of Psychoanalytic Psychotherapy in the Somatoform Disorders Treatment,” Feb. 2018, doi: 10.26226/morressier.5a7070ded462b80290b56a4a.

N. Nacca, D. Vatti, R. Sullivan, P. Sud, M. Su, and J. Marraffa, “The Synthetic Cannabinoid Withdrawal Syndrome,” J Addict Med, vol. 7, no. 4, pp. 296–298, Jul. 2013, doi: 10.1097/adm.0b013e31828e1881.

R. W. Lam, “Clinical features and diagnosis,” in Depression, Oxford University Press, 2018, pp. 23–34. doi: 10.1093/med/9780198804147.003.0004.

D. Ranđelović, “The Co-occurrence of Non-suicidal Self-injury and Attempted Suicide Among Adolescents Hospitalized in Clinic for Mental Disorders ‘Dr Laza Lazarevic,’” Feb. 2017, doi: 10.26226/morressier.588f064fd462b8028d891e2c.

B. Sichère, “Shakespeare, lointain et proche,” in Shakespeare, lointain et proche, Hermann, 2023, pp. 223–229. doi: 10.3917/herm.vigna.2023.01.0223.

L. Jarrell, “Therapeutic management of atopic dermatitis,” Nurse Pract, vol. 49, no. 6, pp. 39–46, May 2024, doi: 10.1097/01.npr.0000000000000183.

A. Shehatah, M. A. Rabie, and A. Al-Shahry, “Prevalence and correlates of depressive disorders in elderly with type 2 diabetes in primary health care settings,” J Affect Disord, vol. 123, no. 1–3, pp. 197–201, Jun. 2010, doi: 10.1016/j.jad.2009.09.002.

R. L. Nail and L. M. Dean, “Drug abuse: A manifestation of the cyclic nature of human behavior,” Drug Alcohol Depend, vol. 1, no. 6, pp. 429–434, Oct. 1976, doi: 10.1016/0376-8716(76)90007-7.

F. Hasan Alam, N. Hassan, S. El-Azzab, and S. El-Azzab, “Effect of Activity Therapy on Symptoms and Quality of Life among Patients with Paranoid Schizophrenia,” Port Said Scientific Journal of Nursing, vol. 10, no. 2, pp. 1–28, Jun. 2023, doi: 10.21608/pssjn.2023.210237.1258.

M. M. Mirkhamzaevna and A. Viloyathon, “INTRODUCTION OF PATIENTS WITH CHRONIC CEREBROVASCULAR DISEASE CAUSED BY ARTERIAL HYPOTENSION, IN PATIENTS OF YOUNG AGE,” Frontline Medical Sciences and Pharmaceutical Journal, vol. 02, no. 04, pp. 47–52, Apr. 2022, doi: 10.37547/medical-fmspj-02-04-07.

R. Bryant-Waugh, “Anorexia nervosa in children and adolescents,” in Eating Disorders in Children and Adolescents, Cambridge University Press, 2001, pp. 111–122. doi: 10.1017/cbo9780511543890.009.

O. H. Al-Jiffri, “Association Between the Immune System Response and Body Mass Index Among Hepatitis C Virus Saudi Patients,” European Journal of Basic Medical Sciences, vol. 5, no. 4, pp. 61–66, Dec. 2015, doi: 10.21601/ejbms/9174.

I. Chaudhuri, Y. Ngiewih, L. Levy, and R. J. McCunney, “Comment on Balwierz et al. Potential Carcinogens in Makeup Cosmetics. Int. J. Environ. Res. Public Health 2023, 20, 4780,” Int J Environ Res Public Health, vol. 20, no. 19, p. 6901, Oct. 2023, doi: 10.3390/ijerph20196901.

G. Singh and L. Samavedham, “Unsupervised learning based feature extraction for differential diagnosis of neurodegenerative diseases: A case study on early-stage diagnosis of Parkinson disease,” J Neurosci Methods, vol. 256, pp. 30–40, Dec. 2015, doi: 10.1016/j.jneumeth.2015.08.011.

P.-A. Fabre and B. Pierre, “Les Jésuites,” in Les Jésuites, Bouquins, 2023, pp. 1133–1136. doi: 10.3917/bouq.fabre.2022.01.1133.

T. Turayev, “THE MODERN CONDITION OF THE DARK SEROZEMS OF THE AKTAU MOUNTAIN NURATA DISTRICT,” Pochvovedenie i agrokhimiya, no. 4, pp. 17–23, 2021, doi: 10.51886/1999-740x_2021_4_17.

O. Smith, Mind Maps for Medical Students Clinical Specialties. CRC Press, 2017. doi: 10.1201/9781315385235.

P. Jolicoeur and S. M. Kosslyn, “Coordinate systems in the long-term memory representation of three-dimensional shapes,” Cogn Psychol, vol. 15, no. 3, pp. 301–345, Jul. 1983, doi: 10.1016/0010-0285(83)90011-7.

V. K. Abdullaeva, “FEATURES OF PSYCHO-EMOTIONAL CHANGES IN WOMEN DURING PREGNANCY,” Theoretical & Applied Science, vol. 46, no. 02, pp. 122–124, Feb. 2017, doi: 10.15863/tas.2017.02.46.22.

S. E. Hall, G. Rayner, and S. J. Wilson, “Cognitive Rehabilitation of Traumatic Brain Injury and Post-traumatic Epilepsy,” in Post-traumatic Epilepsy, Cambridge University Press, 2021, pp. 104–127. doi: 10.1017/9781108644594.010.

S.-H. Lee, “Symptoms and Signs of Hemorrhagic Stroke,” in Stroke Revisited: Hemorrhagic Stroke, Springer Singapore, 2018, pp. 103–108. doi: 10.1007/978-981-10-1427-7_8.

E. Biktimirov and L. Biktimirova, “Media matters: Understanding the impact of media coverage on the Bitcoin market,” Research Features, 2024, doi: 10.26904/rf-153-6806074983.

B. Barahona-Corrêa, “The High-Functioning Group: High-Functioning Autism and Asperger Syndrome in Adults,” in Autism Spectrum Disorders in Adults, Springer International Publishing, 2017, pp. 129–178. doi: 10.1007/978-3-319-42713-3_5.

A. K. Bachu, “Mal de Débarquement Syndrome Complicated by Psychiatric Comorbidities: Response to Maruta et al,” Prim Care Companion CNS Disord, vol. 25, no. 4, Jul. 2023, doi: 10.4088/pcc.23lr03518a.

A. Zabotina, A. Taraskina, and E. Krupitsky, “Risk for antipsychotic-induced extrapyramidal symptoms: a focus on monoamine receptors on peripheral blood lymphocytes,” Sep. 2018, doi: 10.26226/morressier.5b681761b56e9b005965c39d.

E. Kraepelin, “Lecture VIII: Mixed conditions of maniacal-depressive insanity.,” in Lectures on clinical psychiatry., William Wood & Co, 1904, pp. 68–76. doi: 10.1037/10789-008.

J. Mrizak, S. A. M. I. Ouanes, M. Lakhal, R. Y. M. Rafrafi, and Z. El-Hechmi, “EPA-1205 – Remission and recovery in schizophrenia: associated socio-demographic and clinical features,” European Psychiatry, vol. 29, p. 1, 2014, doi: 10.1016/s0924-9338(14)78451-2.