MODERN METHODS OF DIAGNOSING AND TREATING NEUROLOGICAL CHANGES OBSERVED IN ALCOHOLISM

Niyozov Shuxrat Toshtemirovich; Mamurova Mavludaxon Mirxamzayevna; Turayev Bobir Temirpulotovich

doi:10.61796/jmgcb.v2i1.1203

Authors

Niyozov Shuxrat Toshtemirovich
niyozov@gmail.com
Samarkand State Medical University, Uzbekistan
Mamurova Mavludaxon Mirxamzayevna Doctor of Philosophy (PhD) of the Department of Neuralogy, Samarkand State Medical University, Samarkand, Republic of Uzbekistan
Turayev Bobir Temirpulotovich Assistant of the Department of Psychiatry, Medical Psychology and Narcology, Samarkand State Medical University, Samarkand, Republic of Uzbekistan

Vol. 2 No. 1 (2025): Journal of Medical Genetics and Clinical Biology

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January 15, 2025

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Objective: This study aims to explore modern methods of diagnosing and treating neurological changes associated with alcoholism, with a focus on understanding the pathological mechanisms underlying alcohol dependence and its impact on the nervous system. Method: A systematic review of recent clinical studies, diagnostic criteria from DSM-5, and neuroimaging techniques was conducted to evaluate current diagnostic tools and therapeutic approaches. The analysis included neuropsychological assessments, biomarker identification, and pharmacological interventions targeting alcohol-induced neurological impairments. Results: Findings indicate that advanced neuroimaging techniques, such as MRI and PET scans, along with neurocognitive testing, are effective in detecting alcohol-related neurological damage. Pharmacological treatments, including the use of naltrexone, acamprosate, and disulfiram, combined with cognitive-behavioral therapy, show significant efficacy in managing alcohol cravings and mitigating neurological deterioration. Novelty: This study highlights the integration of neuroimaging biomarkers with personalized pharmacological and behavioral interventions as a novel approach for improving diagnostic accuracy and treatment outcomes in patients with alcohol-related neurological changes.

Shuxrat Toshtemirovich, N., Mavludaxon Mirxamzayevna, M., & Bobir Temirpulotovich, T. (2025). MODERN METHODS OF DIAGNOSING AND TREATING NEUROLOGICAL CHANGES OBSERVED IN ALCOHOLISM. Journal of Medical Genetics and Clinical Biology, 2(1), 107–115. https://doi.org/10.61796/jmgcb.v2i1.1203

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