INCIDENCES OF ACUTE APPENDICITIS CAUSED BY VARIOUS PARASITES WITHIN KIRKUK PROVINCE, IRAQ
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Objective: Acute appendicitis (AA) may initiate due to various agents including bacteria, parasites, mainly Enterobius vermicularis and others meanwhile studies on its etiology are so rare in Iraq. Method: This research involves 50 specimen undergone appendectomies presented with clinical symptoms of AA investigated for various parasites. Results: Four different parasites with various proportions were detected in the 50 appendectomies patients. Almost 27(54%) of cases were diagnosed negative or non-parasitic infection while only 23(46%) were diagnosed infected with various parasites e.g. Entamoeba histolytica, with highest prevalence 12(24%); followed by Enterobius vermicularis with 8(16%); Blantidium coli 2(4%) and finally Ascaris lumbricus 1(2%). Novelty: The percentage of infection by E. vermicularis denotes the highest international record as the main cause of acute appendicitis worldwide which might be interpreted as a most pandemic parasite in poor food hygiene conditions in Iraq. Appendicitis displayed almost no impact on blood parameters. Extra parameters should be adopted to monitor the hygiene of Iraqi local restaurants or takeaways serve the exposed food for public consumption.
A. L. Hamilton, M. A. Kamm, S. C. Ng and M. Morrison, “Proteus spp. as Putative Gastrointestinal Pathogens.” Clin Microbiol Rev. 31(3): e00085-17, 2018. doi: 10.1128/CMR.00085-17.
D. A. G. Lor, A. A. Bazzaz, N. A. Chelebi, and S. A. Bazzaz, “Does expression of substance-P in normal appendices confirm the neuroimmune appendicitis or disprove the negative appendectomy?” Journal of Population Therapeutics & Clinical Pharmacology. 30(3): e331–e345; 2021. DOI: 10.47750/jptcp.2023.30.03.035.
A. A. Bazzaz, D. A. G. Lor, and N. B. Mahdi, “Impact of Some Antibiotics on Bacteria Isolated from Appendices in Kirkuk Province, Iraq’. Advances in Bioscience and Biotechnology; 9: 1-10. 2018. http://www.scirp.org/journal/abb. ISSN Online: 2156-8502. ISSN Print: 2156-8456.
B. Killinger, and V. Labrie, “The appendix in Parkinson’s disease: from vestigial remnant to vital organ?” Parkinsons Dis. 9(s2): S345-S358. 2019.doi:10.3233/JPD-191703.
L. Vitetta, J. Chen, and S. Clarke, “The vermiform appendix: an immunological organ sustaining a microbiome inoculum”. Clinical Science (Lond). 133(1): 1-8. 2019. doi:10.1042/CS20180956.
D. G. Addiss, N. Shaffer, B. S. Fowler, and R. V. Tauxe, “The epidemiology of appendicitis and appendectomy in the United States”. Am J Epidemiol. 132: 910-25. 1990.
S. Ipatenco, “Can Spicy Food Cause Your Appendix to Burst?” AZ Central, 2017. http://healthyliving.azcentral.com/can-spicy-food-cause-appendix-burst-19252.html.
P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken, “Manual of clinical microbiology,” 8th Ed., vol. 2., p: 2031-2034. ASM Press, Washington, DC. 2003.
E. Efraimidou, A. Gatopoulou, C. Stamos, N. Lirantzopoulos, and G. Kouklakis, “Enterobius Vermicularis infection of the appendix as a cause of acute appendicitis in a Greek adolescent”: a case report. Cases Journal. 1(1): 376. 2018 doi: 10.1186/1757-1626-1-376.
J. A. Antilahy, M. Akhoundi, M. Belaloui, A. Borovkov, A. Marteau, E. Bonte, and A. Izri, “ Acute appendicitis caused by Enterobius vermicularis” Observations from a case report. 12: 25:e01227. 2012. doi: 10.1016/j.idcr.2021.e01227. Also available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8319506/
. D. Elliot, “Intestinal Worms. In Sleisenger and Fortdtran's Gastrointestinal and liver disease”. 2. 8th edition. Edited by: Feldman M, Friedman L, Brandt L. Philadelphia: Elsevier Sauders; 2442-2443. 2016.
. D. F. de Silva, R. J. da Silva, M. G. da Silva, A. C. Sartorelli, and M. A. Rodrigues, “Parasitic infection of the appendix as a cause of acute appendicitis”. Parasitology Research. 102: 99-102. 2007.
K. Bharathi, S. Anuradha, V. C. Ajay-Chandrasekar, and R. Thirunarayanan, “Enterobius vermicularis worm granuloma mimicking like a pseudo tumor in the anal canal: An unusual clinical presentation.” Tropical Parasitology. 2(2): 124-126. 2012. doi: 10.4103/2229-5070.105178.
L. Ghan-Shyam, L. Tan-Figueroa, F. M. Crinella, and S. Lohiya, ”Epidemiology and control of enterobiasis in a developmental center’. West J Med. 172(5): 305-308. 2000. doi: 10.1136/ewjm.172.5.305.
S. S. A. K. Alsaqi, and Z. M. Jasim, “Histopathological study of acute and chronic appendicitis in patents from Babylon”. European Journal of Modern Medicine and Practice. 5(1): 1-10. 2025. https://inovatus.es/index.php/ejmmp/Guidelines.
B. Birnbaum and R. Stephanie, “Appendicitis at the millennium”. Radiology Journal; 215: 337–348. 1999.
A. Wysocki, L. Bolt, and M. Poźniczek, “Changing views in the 20th century regarding acute appendicitis”. Aroh, Histo. Fiolz. Med.J; 63(3-4): 258-264. 2000.
O. Aydin, “Incidental parasitic infestations in surgically removed appendices: a retrospective analysis”. Diagnostic Pathology. 2: 16-25. 2007.
W. Y. Lau, C. H. Teoh-Chan, S. T. Fan, W. C. Yam, and S. H. Wong, “The bacteriology and septic complication of patients with appendicitis”. Ann Surg. 200(5): 576–581. 1984. doi: 10.1097/00000658-198411000-00003.
A. Nugusse, H. Amu Mitiku, T. B. Raru, M. Abdurke, J. Yousif, A. Brewis, A and K. T. Roba, . Correlates of undernutrition of children (Aged 5–14 Years) in Haramaya District, Eastern Ethiopia. Human Nutrition and Metabolism; Volume 29 Pagination 200157. 2022. ISSN: 2666-1497.
M. J. Arca, R. L. Gates, J. I. Groner, S. Hammond, D. A. Caniano, “Clinical manifestations of appendiceal pinworms in children: an institutional experience and a review of the literature”. Pediatr Surg. Int. 20: 372-380. 2004.
E. Efraimidou, A. Gatopoulou, C. Stamos, N. Lirantzopoulos, and G. Kouklakis, “The Enterobius Vermicularis infection of the appendix as a cause of acute appendicitis in a Greek adolescent: a case report, Cases Journal. 1: 376. 2008. doi:10.1186/1757-1626-1-376 375.
S. Panidis, D. Paramythiotis, D. Panagiotou, G. Batsis, S. Salonikidis, V. Kaloutsi, A. Michalopoulos, "Acute appendicitis secondary to Enterobius vermicularis infection in a middle-aged man: a case report". Journal of Medical Case Reports. 5 559. 2011. doi:10.1186/1752-1947-5-559.
S. Wang, Z. Yao, Y. Hou, D. Wang, H. Zhang, J. Ma, L. Zhang, and S. Liu, “Prevalence of Enterobius vermicularis among preschool children in 2003 and 2013 in Xinxiang city, Henan province, Central China”. Parasite. 23: 30. 2016.
A. Hall, K. S. Anwar, A. Tomkins, and L. Rahman, "The distribution of Ascaris lumbricoides in human hosts: A study of 1765 people in Bangladesh". Transactions of the Royal Society of Tropical Medicine and Hygiene. 93(5): 503–510. 1999. doi:10.1016/s0035.
Y. Dongjian, Y. Ya, W. Yingjian, Y. Yu, D. Shurong, C. Yue, J. Qingwu, Z. Yibiao, "Prevalence and Risk Factors of Ascaris lumbricoides, Trichuris trichiura and Cryptosporidium Infections in Elementary School Children in Southwestern China: A School-Based Cross-Sectional Study". Int J Environ Res Public Health. 15(9): 1809. 2018. doi:10.3390/ijerph15091809.
A. F. Read, and A. Sharping, “The evolution of tissue migration by parasitic nematode larvae". Parasitology. 111(3): 359-371.1995.
Copyright (c) 2025 Ayoub A. Bazzaz, Ruwaida E. Shaaban, Sa’ad A.Y. Kopurlu, Nada T. Al-Basheer, Noorhan A. Chelebi
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